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首頁 > 產品中心 > 抗體 > 其它一抗 > abs171777Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

簡要描述:Rabbit anti-CD278/ICOS Recombinant Monoclonal Antibody(R104),儲存溶液:PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 產品型號:abs171777
  • 廠商性質:生產廠家
  • 更新時間:2024-07-07
  • 訪  問  量:1149

詳細介紹

品牌absinCAS-
分子式-純度-
分子量-貨號abs171777
規格100uL供貨周期現貨
主要用途IHC-P: 1:500應用領域化工,生物產業,綜合
概述
別名
Inducible T-cell costimulator; AILIM
宿主
Rabbit
反應種屬
Human
應用
IHC-P: 1:500
性能
形式
Liquid
濃度
0.5 mg/ml
純化方法
Protein A affinity column
類型
Monoclonal Antibody
克隆號
R104
儲存/保存方法
Store at -20℃ for one year.
存儲溶液
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
靶標
背景說明
Inducible T cell costimulatory factor (ICOS, cluster of differentiation, CD278) is an activated costimulatory immune checkpoint expressed on T cells. Its ligand ICOSL was expressed in antigen-presenting cells and somatic cells (including tumor cells in the tumor microenvironment) [PMID: 28713380, PMID: 12800259]. As one of the most common targeted immune checkpoints, ICOS is considered a possible way to develop new immunotherapy [PMID: 29544515]. Some clinical studies shown that blocking ICOS alone can inhibit tumor growth and proliferation, as well as TIGIT, CTLA4, and PD-1 [PMID: 30232519, PMID: 28803728].
細胞定位
Cell Membrane, Secreted
UniProt
Q9Y6W8
實驗結果圖
IHC shows positive staining in paraffin-embedded human thymus. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
Negative control: IHC shows negative staining in paraffin-embedded human kidney. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
溫馨提示:本產品僅作科研實驗使用,不支持臨床等研究

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